No. 22 Louisville looks to follow up its dominant opening game with a similar effort against Jacksonville State

Jacksonville State (0-1) vs. No. 22 Louisville (1-0), Saturday, 3:30 p.m. ET (ACCNX)

MGM Plant College football odds: Louisville at 30 1/2.

Record of the series: First meeting.

WHAT IS IT ABOUT?

Newly ranked Louisville is looking for another dominant performance after crushing FCS Austin Peay 62-0 in its opener, while Jacksonville State looks to rebound from a 55-27 loss to Coastal Carolina on Aug. 29 and beat its first ACC opponent since beating Florida State in 2021.

A key clash

Texas Tech transfer Tyler Shough made his debut at quarterback for Louisville and completed 18 of 24 passes for 232 yards and four touchdowns in the first half against Austin Peay. Backups Harrison Bailey and Pierce Clarkson combined to complete 9 of 10 passes for 46 yards, and all three combined to hit 15 receivers with at least one pass. Jacksonville State allowed Coastal Carolina to throw for 258 yards and three scores last week, including TD passes of 36 and 37 yards. The Gamecocks also did not record a sack, increasing their challenge of slowing down a Cardinals offense with depth at the receiver position and a seasoned QB.

PLAYERS TO WATCH

Jacksonville State defensive end J-Rock Swain has 140 tackles in 45 games over five seasons, including three stops last week against Coastal Carolina. He has 72 solo tackles and 68 assists and was named to the All-Conference USA team last season. Swain was also named to the Atlantic Sun and Ohio Valley All-Conference teams.

Louisville running back Isaac Brown ran for 77 TD yards and 123 yards on five attempts, the best debut by a freshman in school history. He also became the first true freshman on the Cardinals to run for a score since Keyjuan Brown against Murray State early last season. The Cardinals rushed for 293 yards against the Governors — 204 after halftime — and averaged 10.5 yards per attempt.

FACTS AND FIGURES

Jax State coach Rich Rodriguez was 2-1 against Louisville while coaching West Virginia. … Junior defensive back Pat Taylor, a transfer from Georgia, debuted with 12 tackles against CCU. … Defensive end Zechariah Poyser recovered a fumble and intercepted a pass last week. … Louisville’s 571 yards of offense against APSU were the fifth-most in an opening game. … DB Devin Neal and LB Dan Foster Jr. blocked punts, the first time Louisville had done so since 2004 against Cincinnati.

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